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Table 3 The 50 features based on ChIP-seq intensity of four histone marks (H3K27ac, H3K4me1, H3K4me3 and H3K27me3) and RNA polymerase II phosphorylation at serine 5 (RNAP)

From: Inferring dynamic gene regulatory networks in cardiac differentiation through the integration of multi-dimensional data

No. Histone Description Dir. P value Signif.
20 H3K27ac mean(xt,1000) + 4.40E-245 ***
21 mean(xt,500) - 7.63E-03 **
22 mean(xt,100) - 1.59E-21 ***
23 mean(xt,50) + 2.41E-06 ***
24 mean(xt,10) - 2.09E-01  
25 mean(xt+1,1000)-mean(xt,1000) - 1.62E-04 ***
26 mean(xt+1,500)-mean(xt,500) - 9.25E-01  
27 mean(xt+1,100)-mean(xt,100) - 1.03E-03 **
28 mean(xt+1,50)-mean(xt,50) + 6.40E-04 ***
29 mean(xt+1,10)-mean(xt,10) - 1.33E-01  
30 H3K4me1 mean(xt,1000) + 9.27E-01  
31 mean(xt,500) + 2.04E-07 ***
32 mean(xt,100) + 1.04E-01  
33 mean(xt,50) - 8.89E-01  
34 mean(xt,10) - 3.06E-01  
35 mean(xt+1,1000)-mean(xt,1000) - 1.21E-56 ***
36 mean(xt+1,500)-mean(xt,500) + 2.42E-17 ***
37 mean(xt+1,100)-mean(xt,100) + 4.97E-05 ***
38 mean(xt+1,50)-mean(xt,50) - 4.04E-01  
39 mean(xt+1,10)-mean(xt,10) + 8.39E-01  
40 H3K4me3 mean(xt,1000) - 3.34E-91 ***
41 mean(xt,500) + 2.34E-32 ***
42 mean(xt,100) + 1.28E-02 *
43 mean(xt,50) - 8.41E-01  
44 mean(xt,10) + 7.33E-01  
45 mean(xt+1,1000)-mean(xt,1000) - 3.73E-23 ***
46 mean(xt+1,500)-mean(xt,500) + 3.82E-01  
47 mean(xt+1,100)-mean(xt,100) + 3.15E-04 ***
48 mean(xt+1,50)-mean(xt,50) + 9.68E-01  
49 mean(xt+1,10)-mean(xt,10) - 7.65E-01  
50 H3K27me3 mean(xt,1000) + 1.61E-15 ***
51 mean(xt,500) - 1.83E-27 ***
52 mean(xt,100) + 7.01E-02  
53 mean(xt,50) - 2.04E-01  
54 mean(xt,10) - 8.98E-02  
55 mean(xt+1,1000)-mean(xt,1000) + 1.77E-08 ***
56 mean(xt+1,500)-mean(xt,500) - 9.39E-05 ***
57 mean(xt+1,100)-mean(xt,100) + 2.15E-01  
58 mean(xt+1,50)-mean(xt,50) - 3.05E-01  
59 mean(xt+1,10)-mean(xt,10) - 4.10E-01  
60 RNAP mean(xt,1000) - 0.00E + 00 ***
61 mean(xt,500) + 1.82E-105 ***
62 mean(xt,100) + 1.04E-13 ***
63 mean(xt,50) - 1.54E-01  
64 mean(xt,10) + 9.46E-01  
65 mean(xt+1,1000)-mean(xt,1000) - 6.44E-166 ***
66 mean(xt+1,500)-mean(xt,500) + 1.98E-31 ***
67 mean(xt+1,100)-mean(xt,100) + 5.17E-03 **
68 mean(xt+1,50)-mean(xt,50) - 4.77E-01  
69 mean(xt+1,10)-mean(xt,10) + 1.96E-01  
  1. *: 0.01 ≤p value < 0.05; **: 0.001≤p value < 0.01; ***: p value < 0.001.