Discovery of prognostic biomarkers for predicting lung cancer metastasis using microarray and survival data

BMC Bioinformatics

Table 1 Selected characteristics of participants according to NSCLC

Characteristics		Number (N = 78)	%	Metastasis		p ^a
Characteristics		Number (N = 78)	%	+	-	p ^a
Age
	≧65	49	63	25	24	0.64
	<65	29	37	17	12
Sex
	Male	56	72	28	28	0.32
	Female	22	28	14	8
Smoking index
	≧20 pack-year	35	45	17	18	0.49
	<20 pack-year	43	55	25	18
Histologic type
	Squamous cell	25	32	11	14	0.46^b
	Adenocarcinoma	46	59	25	21
	Large cell	5	6	4	1
	Other cell type	2	3	2	0
Differentiation
	Well	5	6	1	4
	Moderate	51	65	28	23	0.80^b
	Poor	22	28	13	9
Tumor size
	≧5 cm	18	23	11	7	0.59
	<5 cm	59	76	31	28
pN status
	Positive	54	69	25	29	0.09
	Negative	25	32	17	7
pM status
	Positive	5	6	5	0	0.20
	Negative	73	94	37	36
Pathologic stage
	Stage I	36	46	10	26	3.0E-5^c
	Stage II	11	14	7	4
	Stage III	26	33	20	6
	Stage IV	5	6	5	0

^aThe two-sided p-values were calculated by Fisher's exact test.
^bThe p-values were calculated using the two variables with the largest numbers of patients.
^cThe p-value was calculated to measure the association between two variables (Stage I and Stages II, III and IV).

ISSN: 1471-2105