Identifying restrictions in the order of accumulation of mutations during tumor progression: effects of passengers, evolutionary models, and sampling

Table 6 Frequencies of most common confidence sets using multiple comparisons with the best with a coverage of 0.90, when drivers are unknown

Confidence sets	Conjunction				No conjunction
	Diff	PFD	PND	FPF	Diff	PFD	PND	FPF
S1:OT-A, S5:OT-A	0.01	-	0.04	-	0.01	-	0.07	-
S1:OT, S1:OT-A	0.07	0.07	0.11	-	0.08	0.07	0.22	-
S1:OT-A	0.02	-	0.06	-	0.02	-	0.05	-
S5:OT-A	0.05	-	-	-	0.06	-	-	-
S5:OT, S5:OT-A	0.10	0.03	-	-	0.12	0.02	-	-
S5:DiP, S5:DiP-A, S5:OT, S5:OT-A	0.04	-	-	-	0.05	-	-	-
S1:OT, S1:OT-A, S5:OT, S5:OT-A	0.02	-	0.02	-	0.05	-	0.07	-
J5:OT, J5:OT-A, S5:OT, S5:OT-A	0.01	0.06	-	-	-	0.04	-	-
S1:CBN, S1:CBN-A	0.01	-	0.05	-	0.01	0.01	0.01	-
S1:CBN, S1:CBN-A, S1:OT, S1:OT-A	-	0.01	0.25	-	0.02	-	0.14	-
J1:DiP, J1:OT, J5:DiP, J5:OT, S1:DiP, S5:DiP, S5:OT	-	0.02	-	0.04	-	0.03	-	0.05

Combinations not shown have a frequency less than 0.05 for all columns or are composed of more than 10 individual best methods. Frequencies normalized by column total (N = 432). ‘A:B’ denotes filtering with A and using method B.

ISSN: 1471-2105