Figure 3
From: The acquisition of novel N-glycosylation sites in conserved proteins during human evolution
Multiple sequence alignments of human-specific N-glycosylation sites. The human-specific N-glycosylation modification sites and the surrounding regions for APMAP (A), CD166 (B), and thyroglobulin (C) proteins are presented. The N-glycosylation consensus sequences are highlighted in cyan. An adjacent N-glycosylation site (Asn-95) that is found in CD166 and is well conserved among mammals is indicated by plus signs (+++). The residues that are identical to those in the human sequence are indicated by dots (.). Dashes (−) denote alignment gaps. In some species, sequences were not determined. hum, humans; hac, humans and chimpanzees; aga, African great apes; gra, great apes; ape, apes; cat, catarrhines; sim, simians; pri, primates; eua, Euarchonta; gli, Glires; lau, Laurasiatheria; afr, Afrotheria; xen, Xenarthra; mar, Marsupialia; and mon, Monotremata.