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Table 4 31 highest scoring C. elegans genes that received HyQue evaluation scores for their role in aging without existing aging-related annotations, and the data evaluation functions that contributed to their scores

From: An evidence-based approach to identify aging-related genes in Caenorhabditis elegans

WormBase identifier

Symbol

Satisfied data evaluation function

1

2

3

4

5

6

7

8

9

WBGene00000252

bli-2

 

✓

    

✓

✓

✓

WBGene00000255

bli-5

 

✓

   

✓

 

✓

✓

WBGene00000262

bra-1

 

✓

    

✓

✓

✓

WBGene00000479

cgh-1

     

✓

✓

✓

✓

WBGene00000915*

daf-21

     

✓

✓

✓

✓

WBGene00001165

efn-4

 

✓

    

✓

✓

✓

WBGene00001428*

fkb-3

 

✓

   

✓

 

✓

✓

WBGene00001543*

gcy-18

 

✓

   

✓

 

✓

✓

WBGene00001578

ges-1

 

✓

   

✓

 

✓

✓

WBGene00001746

gsk-3

 

✓

    

✓

✓

✓

WBGene00001824

hbl-1

 

✓

   

✓

 

✓

✓

WBGene00001974

hmg-4

 

✓

    

✓

✓

✓

WBGene00001979

hmp-2

 

✓

    

✓

✓

✓

WBGene00002005*

hsp-1

   

✓

 

✓

 

✓

✓

WBGene00002013*

hsp-12.6

 

✓

 

✓

   

✓

✓

WBGene00002069*

ikb-1

 

✓

 

✓

   

✓

✓

WBGene00002881

let-756

 

✓

    

✓

✓

✓

WBGene00003029

lin-44

 

✓

    

✓

✓

✓

WBGene00003058

lov-1

 

✓

    

✓

✓

✓

WBGene00003210

mel-28

     

✓

✓

✓

✓

WBGene00003473

mtl-1

 

✓

   

✓

 

✓

✓

WBGene00003497

mup-4

 

✓

    

✓

✓

✓

WBGene00003977*

pes-2.1

 

✓

   

✓

 

✓

✓

WBGene00004392

rnr-2

     

✓

✓

✓

✓

WBGene00004765

sel-8

 

✓

    

✓

✓

✓

WBGene00006789

unc-54

 

✓

    

✓

✓

✓

WBGene00007036

sod-5

 

✓

   

✓

 

✓

✓

WBGene00016140

rpb-2

     

✓

✓

✓

✓

WBGene00017830

rpb-8

 

✓

    

✓

✓

✓

WBGene00020100

mks-1

 

✓

   

✓

 

✓

✓

WBGene00021334

vps-4

 

✓

    

✓

✓

✓

  1. * = true positive.