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Table 2 The number and percentage of the mutant isolates with the structural or functional abnormalities in the genotypes

From: Mutations and CpG islands among hepatitis B virus genotypes in Europe

Genotypes Mutant isolates with abnormalities Types of abnormalities
No. %*
A 26 96% (1) The truncated proteins including pre-C/C, pre-S1/pre-S2/S and X proteins; (2) the nonfunctional proteins including pre-C/C, pre-S2/S and X proteins; (3) the proteins containing aa internal deletion including pre-C/C and pre-S1/pre-S2/S proteins; (4) X gene containing a point mutation which resulted in a premature stop codon.
26/27
D 27 29% (1) The truncated proteins including pre-C/C, pre-S1/pre-S2/S and X proteins; (2) the nonfunctional proteins including pre-C/C, pre-S1/pre-S2/S, X proteins and polymerase; (3) the proteins containing aa internal deletion including pre-C/C and pre-S1/pre-S2/S proteins; (4) pre-C/C and X genes containing a point mutation which resulted in a premature stop codon; (5) some pre-C/C genes were pseudogenes.
27/93
E 2 100% (1) The truncated pre-C/C protein; (2) the nonfunctional proteins including pre-C/C, polymerase and large S proteins.
2/2
G 4 80% (1) The truncated X protein; (2) the nonfunctional pre-C/C protein; (3) pre-C/C containing a premature stop codon.
4/5
  1. *The percentage is equal to number of the mutant isolates with the structural or functional abnormalities/number of total mutant isolates × 100%.
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