Table 4 Distribution of CpG islands in HBV genotypes A-G
From: Mutations and CpG islands among hepatitis B virus genotypes in Europe
Genotype | Three-conventional CpG islands | Two-conventional CpG islands | Novel CpG islands | |||
|---|---|---|---|---|---|---|
number | % | number | % | number | % | |
A total | 115 | 76.66% | 31 | 20.67% | 4 | 2.67% |
(n = 150) | ||||||
A normal | 100 | 81.30% | 21 | 17.07% | 2 | 1.63% |
(n = 123) | ||||||
A mutant | 15 | 55.56% | 10 | 37.04% | 2 | 7.40% |
(n = 27) | ||||||
B total | 4 | 66.7% | 2 | 33.3% | 0 | 0 |
(n = 6) | ||||||
B normal | 4 | 66.7% | 2 | 33.3% | 0 | 0 |
(n = 6) | ||||||
B mutant | 0 | 0 | 0 | 0 | 0 | 0 |
(n = 0) | ||||||
C total | 1 | 100% | 0 | 0 | 0 | 0 |
(n = 1) | ||||||
C normal | 1 | 100% | 0 | 0 | 0 | 0 |
(n = 1) | ||||||
C mutant | 0 | 0 | 0 | 0 | 0 | 0 |
(n = 0) | ||||||
D total | 135 | 68.53% | 59 | 29.95% | 3 | 1.52% |
(n = 197)* | ||||||
D normal | 71 | 66.98% | 34 | 32.08% | 1 | 0.94% |
(n = 106) | ||||||
D mutant | 64 | 70.33% | 25 | 27.47% | 2 | 2.20% |
(n = 91)* | ||||||
E total | 8 | 61.54% | 3 | 23.08% | 2 | 15.38% |
(n = 13)* | ||||||
E normal | 8 | 66.66% | 2 | 16.67% | 2 | 16.67% |
(n = 12) | ||||||
E mutant | 0 | 0 | 1 | 100% | 0 | 0 |
(n = 1)* | ||||||
F total | 0 | 0 | 2 | 100% | 2 | 100% |
(n = 2) | ||||||
F normal | 0 | 0 | 2 | 100% | 2 | 100% |
(n = 2) | ||||||
F mutant | 0 | 0 | 0 | 0 | 0 | 0 |
(n = 0) | ||||||
G total | 0 | 0 | 11 | 100% | 0 | 0 |
(n = 11) | ||||||
G normal | 0 | 0 | 6 | 100% | 0 | 0 |
(n = 6) | ||||||
G mutant | 0 | 0 | 5 | 100% | 0 | 0 |
(n = 5) | ||||||
Sum | 263 | 69.21% | 108 | 28.42% | 11** | 2.89% |