Genotype
|
Island I
|
Island II
|
Island III
|
Island IV
|
Island V
|
---|
LD-Y
|
LD-N
|
LD-Y
|
LD-N
|
LD-Y
|
LD-N
|
LD-Y
|
LD-N
|
LD-Y
|
LD-N
|
---|
A
|
+
|
+
|
-
|
+
|
-
|
+
|
-
|
+
|
-
|
-
|
D
|
+
|
+
|
-
|
+
|
+
|
+
|
+
|
-
|
-
|
-
|
E
|
-
|
-
|
-
|
+
|
-
|
+
|
-
|
+
|
-
|
-
|
G
|
-
|
-
|
-
|
+
|
-
|
+
|
-
|
-
|
-
|
-
|
- All functional or structural abnormalities of HBV genes are observed in the mutant isolates not in the normal isolates.
- LD-Y: lengths of CpG islands between normal and mutant isolates are different. LD-N: lengths of CpG islands between normal and mutant isolates are not different. +: The functional or structural abnormalities of HBV genes are observed; −: The functional or structural abnormalities of HBV genes are not observed.