Mutations and CpG islands among hepatitis B virus genotypes in Europe

BMC Bioinformatics

Table 7 The relationship between the abnormalities and length differences of CpG islands and mutations in HBV Genotypes A-G

Genotype	Island I		Island II		Island III		Island IV		Island V
Genotype	LD-Y	LD-N	LD-Y	LD-N	LD-Y	LD-N	LD-Y	LD-N	LD-Y	LD-N
A	+	+	-	+	-	+	-	+	-	-
D	+	+	-	+	+	+	+	-	-	-
E	-	-	-	+	-	+	-	+	-	-
G	-	-	-	+	-	+	-	-	-	-

All functional or structural abnormalities of HBV genes are observed in the mutant isolates not in the normal isolates.
LD-Y: lengths of CpG islands between normal and mutant isolates are different. LD-N: lengths of CpG islands between normal and mutant isolates are not different. +: The functional or structural abnormalities of HBV genes are observed; −: The functional or structural abnormalities of HBV genes are not observed.

ISSN: 1471-2105