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Table 7 The relationship between the abnormalities and length differences of CpG islands and mutations in HBV Genotypes A-G

From: Mutations and CpG islands among hepatitis B virus genotypes in Europe

Genotype Island I Island II Island III Island IV Island V
LD-Y LD-N LD-Y LD-N LD-Y LD-N LD-Y LD-N LD-Y LD-N
A + + - + - + - + - -
D + + - + + + + - - -
E - - - + - + - + - -
G - - - + - + - - - -
  1. All functional or structural abnormalities of HBV genes are observed in the mutant isolates not in the normal isolates.
  2. LD-Y: lengths of CpG islands between normal and mutant isolates are different. LD-N: lengths of CpG islands between normal and mutant isolates are not different. +: The functional or structural abnormalities of HBV genes are observed; −: The functional or structural abnormalities of HBV genes are not observed.