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Table 2 Empirical power estimates in the absence of population substructure

From: Family-based association analysis: a fast and efficient method of multivariate association analysis with multiple variants

  ρ Q D ' MMASTOR MFBAT MFQLS
Quantitative phenotypes 0.2 2 0 0.5180 0.2025 0.5830
2 0.5 0.7235 0.3750 0.7805
5 0 0.7800 0.3855 0.7870
5 0.5 0.9200 0.6430 0.9240
0.5 2 0 0.4915 0.1655 0.5400
2 0.5 0.6785 0.3340 0.7505
5 0 0.7015 0.3020 0.7350
5 0.5 0.8725 0.5405 0.8885
Dichotomous phenotypes ρ Q D' MMQLS MFBAT MFQLS
0.2 2 0 0.2015 0.0530 0.2340
2 0.5 0.3050 0.1070 0.3470
5 0 0.3205 0.0995 0.3710
5 0.5 0.6215 0.2460 0.6660
0.5 2 0 0.1795 0.0535 0.2130
2 0.5 0.2945 0.0915 0.3270
5 0 0.2670 0.0910 0.3085
5 0.5 0.5200 0.2130 0.5900
  1. The empirical power was estimated using 2,000 replicates at the 0.005 significance level. We assumed that the number of markers was two, and that their minor allele frequencies were 0.2.