Figure 2
From: SCNVSim: somatic copy number variation and structure variation simulator
Homologous sequence mediated SV simulation. The types of homologous sequence (e.g., transposable elements) medicated SV simulated by SCNVSIM are: A) TE-mediated deletion; B) TE-mediated tandem duplication; C) TE-mediated inversion (two TEs are on opposite strands); D) TE-mediated translocation (balanced or unbalanced); and E) TE-mediated insertion (intra- or inter-chromosome). Break points are randomly picked in homologous sequences shared by compatible repeat elements which are from the same repeat family and overlapping with each other.