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Table 3 Most common EGFR mutation types

From: EGFR Mutant Structural Database: computationally predicted 3D structures and the corresponding binding free energies with gefitinib and erlotinib

Mutation types

Number of patients

Percentage

Position (Exon)

L858R

388

41.19%

21

delE746_A750

264

28.03%

19

delL747_P753insS

43

4.56%

19

delE746_S752insV

16

1.70%

19

G719S

10

1.06%

18

delL747_T751

10

1.06%

19

delL747_T751insP

10

1.06%

19

L861Q

10

1.06%

21

G719C

9

0.96%

18

delE746_T751insA

9

0.96%

19