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Table 4 Distribution of mutation types and the number of patients by mutation position

From: EGFR Mutant Structural Database: computationally predicted 3D structures and the corresponding binding free energies with gefitinib and erlotinib

Mutation position Number of occurrences Number of mutation types Number of patients Percentage of all mutation types Percentage of all the patients
Exon 18 ≤3 14 19 12.5% 15.18% 2.02% 4.89%
>3 3 27 2.68% 2.87%
Exon 19 ≤3 26 38 23.21% 32.14% 4.03% 43.41%
>3 10 371 8.93% 39.38%
Exon 20 ≤3 25 34 22.32% 25.89% 3.61% 6.05%
>3 4 23 3.57% 2.44%
Exon 21 ≤3 18 21 16.07% 17.86% 2.23% 44.48%
>3 2 398 1.79% 42.25%
Others ≤3 10 11 8.93% 8.93% 1.17% 1.17%