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Table 5 Mutagenesis results

From: Secondary structural entropy in RNA switch (Riboswitch) identification

Feature

Sensitivity (%)

Specificity (%)

MCC

BJKbp

83.33

83.33

0.645

BJK

75

66.67

0.403

RND

41.67

66.67

0.08

SIL

66.67

16.67

-0.175

  1. Classification rule: Lower value than wild type predicts structural mutant, while higher or equal value predicts non-structural mutants. Positive control: Structural Mutants of a given wild type. Negative control: non-structural mutants of a given wild type. See the Methods section for details on calculating sensitivity and specificity.