network was viewed in Cytoscape and the hub distribution of proteins in the network were analysed. (A) Large hairy ball of the 67,740 non-redundant interactions in the organic view of Cytoscape. (B) Detailed view showing layers of interacting proteins. (C) Pie chart of hub distribution by node class; “Free ends” are defined as have a single interaction, “pipes” have two interactions, and grouped hubs based on numbers of interactions. Numbers in parentheses indicate number of interacting proteins used to determine hub size.