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Figure 4 | BMC Bioinformatics

Figure 4

From: Sigma-RF: prediction of the variability of spatial restraints in template-based modeling by random forest

Figure 4

A comparison of template-based modeling results of T0517 and T0523 by the σ RF and σ native values. The energy landscapes of template-based modeling results of (A) T0517 and (D) T0523 by σ RF , σ Modeller and σ native . The representative structures of low and high TM-score results are superposed: (B) T0517 and (E) T0523. The average restraint energy differences, E RF E native , of the mirror-image structures of (C) T0517 and (F) T0523 evaluated by σ RF and σ native are shown as 3D histogram plots. Positive z-axis values indicate that corresponding distance restraints are favored by σ native and disfavored by σ RF .

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