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Table 5 Lactococcus lactis case study

From: YOC, A new strategy for pairwise alignment of collinear genomes

 

MAUVE

ProgressiveMAUVE

YOC

Lactococcus lactis IL1403 compared to SK11

#Backbone segments

3121

759

165

Mean coverage

64%

77%

79%

Backbone identity%

89%

86%

85%

#included orthologs

370 [27%]

1 173 [85%]

1 287 [92%]

#overlapping orthologs

957 [69%]

193 [14%]

33 [2%]

#excluded orthologs

68

29

75

Orthologs coverage

82.9%

97.4%

95.2%

  1. Basic indicators and biological relevance of three genome alignments (post-processed into backbone segments) produced by MAUVE, ProgressiveMAUVE and YOC for the comparison of two Lactococcus lactis genomes: the subsp. lactis. IL1403 strain genome and the subsp. cremoris. strain SK11 genome. The criteria are the number of backbone segments (#Backbone segments), the mean coverage of the backbone (Mean coverage), the percentage of identity of the backbone (Backbone identity%), the number of orthologs included in the backbone (#included orthologs), overlapping the backbone (#overlapping orthologs) and excluded from the backbone (#excluded orthologs), and the orthologous cumulative length coverage in the backbone (Orthologs coverage) The orthologous genes were extracted from the OMA database [42].