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Table 1 Comparison of the used index structures and memory requirements of evaluated mappers

From: A Long Fragment Aligner called ALFALFA

Mapper

Index type

Adjustable

Size on disk

Peak memory

Construction time

   

(GB)

(GB)

(h:mm)

ALFALFA (s=4)

ESSA

yes

10.7

11.0

0:19

ALFALFA (s=12)

ESSA

yes

5.6

5.7

0:10

Bowtie 2

FM-index

yes

3.9

5.3

1:58

BWA

FM-index

no

5.2

5.4

1:18

CUSHAW3

FM-index

no

3.7

3.5

0:36

GEM

FM-index

yes

4.8

5.0

N.A. §

  1. The ALFALFA index is evaluated for two different sparseness values. The read mappers BWA-SW and BWA-MEM both use the same index structure, jointly reported as BWA. The third column indicates whether memory footprint can be tuned via user-specified options. The fourth column reports the memory footprint of the index structure when stored on disk. The fifth column provides peak memory of the read mapper observed during alignment of 1kbp reads. The time needed to construct the index structure is given in the last column. §A pre-built GEM index was downloaded from the GEM website as the indexer of this mapper ran into a fatal error in our test environment.