Differential co-expression and regulation analyses reveal different mechanisms underlying major depressive disorder and subsyndromal symptomatic depression

Table 3 Identification of 10 TF2taraget DCLs through comparing SSD pre-treatment and healthy control samples

No.	TF	Target	p. DCG	cor.1	cor.2	Type
1	PATZ1 ^*	ADAM17	0.018596	-0.71	0.97	1
2	PATZ1 ^*	CALM3	0.018596	0.03	0.94	0
3	PATZ1 ^*	CIB1	0.018596	0.03	0.93	0
4	TP53	FUS^*	0.001496	-0.47	0.97	1
5	PATZ1 ^*	LOC100130776	0.018596	0.54	-0.97	1
6	CBFB	MACROD2^*	0.029467	-0.53	0.97	1
7	PATZ1 ^*	NLGN2	0.018596	-0.07	-0.94	0
8	PATZ1 ^*	SECISBP2L	0.018596	-0.68	0.97	1
9	PATZ1 ^*	POLD4	0.018596	-0.18	0.97	1
10	PATZ1 ^*	PTMA	0.018596	-0.37	0.97	1

^*Denotes DCG in each TF2target DCL. Some rows were discarded (strikethrough) since they are individual basis. Rows in bold represent the 8 key-DRL_SSD. The p. DCG column denotes the p-value of DCG for each TF2target DCL; the “Cor.1” and “Cor.2” columns represent the correlation coefficients of the two respective conditions. The “Type” column reflects the mode of regulation with “1” denoting a positive/negative regulation in disease samples switched to a negative/positive regulation in control samples and “0” denoting no change in regulation.

ISSN: 1471-2105