Figure 9
From: CHEXVIS: a tool for molecular channel extraction and visualization
The pentameric ligand-gated ion channels extracted in closed and open conformations. The channels are wide and hydrophilic in extra-cellular region which is less conserved. The constricted transmembrane spanning helical channel section is hydrophobic and highly conserved. The bottleneck radius is 2.21Å in closed configuration while it is 5.12Å in open state.