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Table 1 Overview of the validation data sets used in this work

From: MAESTRO - multi agent stability prediction upon point mutations

Data set

Size

Prediction

Validation

Source/Ref.

SP1

2648 mutations

Δ ΔG

5-fold cross validation

[12]

SP2

350 mutations

Δ ΔG

Performance test

[12]

SP3

1925 mutations

Δ ΔG

20-fold cross validation

[5,7]

SP4

1765 mutations

Δ ΔG

10-fold cross validation

ProTherm

MP

479 multi-point mutations

Δ ΔG

10-fold cross validation

ProTherm

SS1

75 disulfide bonds

S-S bond

Performance test

[32]

SS2

15 engineered disulfide bonds

S-S bond

Performance test

[32]