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Table 1 KnowLife relations, their type signatures, and number of seeds

From: KnowLife: a versatile approach for constructing a large knowledge graph for biomedical sciences

Relation

Domain

Range

Seed facts

Affects

Disease

Organ

23

Aggravates

Ecofactor

Disease

21

Alleviates

Drug

Disease

18

Causes

Disease

Disease

70

ComplicationOf

Disease

Disease

5

Contraindicates

Drug

Disease

26

CreatesRisk

Ecofactor

Disease

103

Diagnoses

Device

Disease

29

Interacts

Drug

Drug

9

IsSymptom

Symptom or Disease

Disease

69

ReducesRisk

Drug or Behavior

Disease

24

SideEffect

Symptom or Disease

Drug

12

Treats

Drug

Disease

58