Figure 4

CGC enrichment of the genes identified in breast and other solid cancers. (A) Putative driver genes were detected on the TCGA breast cancer data set by different methods and ranked according to their increasing q values. For each 1–100 top ranked genes (x-axis) the proportion of CGC genes (y-axis) was determined. (B) The average CGC gene proportion of all 9 solid cancers that were analysed for the highest 10, 30 and 100 ranked genes by each method. Error bars indicate standard errors of the mean. The methods are indicated in the legend on the bottom of the figure.