Putative breast cancer genes retrieved by 4 different methods. (A) Venn diagrams indicating the total number of putative breast cancer driver genes retrieved by 4 different methods (method names are indicated on the diagram). (B) Comparison of the significance levels of the genes that were detected by the 4 methods. Genes are ranked according to the product of the q values of the 4 methods together (indicated by the last “combination” column). The colour scale is shown on the bottom right with q values varying from 0.05 (yellow) to 1e-5 or higher (red). Blue boxes indicate non-significant genes.