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Table 6 KEGG pathway enriched by 24 mRNAs targeted by 27 miRNAs, identified by DAVID

From: Principal component analysis-based unsupervised feature extraction applied to in silico drug discovery for posttraumatic stress disorder-mediated heart disease

KEGG pathway

Number of genes

%

P -values

Adjusted P -values

Cardiac muscle contraction

7

30.4

2.30E-09

3.20E-08

Parkinson’s disease

7

30.4

5.80E-08

4.10E-07

Oxidative phosphorylation

6

26.1

2.30E-06

1.10E-05

Alzheimer’s disease

6

26.1

1.20E-05

4.20E-05

Huntington’s disease

6

26.1

1.20E-05

3.50E-05

  1. Number of genes are genes included in pathway, % is the ratio genes included in pathway among 24 genes. P-values and those adjusted by BH criterion were provided by DAVID.
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BMC Bioinformatics

ISSN: 1471-2105

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