The scatterplot of differential expression (DE) and correlation between TRIM22 and every gene in (a) breast cancer state and (b) in normal state. Each point in the plot represents a gene. The x-axis in (a) and (b) represents the correlation coefficients, rN and rD, between TRIM22 and every gene in breast cancer state and normal state respectively. The y-axis represents the DE, t, of the gene. A positive t value indicates a higher gene expression in disease state in compare to normal state, and vice versa, a negative t value indicates a lower gene expression in disease state in compare to normal state. The optimal threshold for DE is drawn using red dash line. Genes found in “cellular response to type I interferon” are highlighted using triangles. Similar to Figure 8, these genes with different DC and DE values are highlighted in different colours: HDC_HDE (red); HDC_LDE (blue); LDC_HDE (green); LDC_LDE (pink).