Table 1 2×2 contingency table for DE and DC

High DE (HDE)

obs _{HDE_LDC}

obs _{HDE_HDC}

obs _HDE

Low DE (LDE)

obs _{LDE_LDC}

obs _{LDE_HDC}

obs _LDE

Marginal total for DC

obs _LDC

obs _HDC