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Table 2 Evaluation of IGH partitioning using inferred genotypes tool

From: HTJoinSolver: Human immunoglobulin VDJ partitioning using approximate dynamic programming constrained by conserved motifs

Database

 

V (%)

D (%)

J (%)

Total (%)

Original

D ≥ 9

3.60 (0.74)

2.30 (2.14)

0.42 (0.0)

6.17

All D

3.60 (0.74)

1.11 (0.99)

0.42 (0.0)

4.91

Updated

D ≥ 9

6.80 (0.28)

0.71 (0.59)

0.53 (0.0)

7.88

All D

6.80 (0.28)

1.25 (1.07)

0.53 (0.0)

8.43

  1. HTJoinSolver alignment of the S22 dataset of human VDJ rearrangements. The percentage of selected germline alleles that is not present in the S22 genotype. In parentheses is the percentage of genes, not just allelic variants, not present in the genotype. HTJoinSolver was evaluated using the original JoinSolver database and a more recently updated germline database from IMGT. The total column is the percentage of V-, D-, or J-germline allele that is not present in the genotype.