Figure 2

Site-specific preferences from deep mutational scanning of a Tn5 transposon. Melnikov et al. [10] performed deep mutational scanning on a Tn5 transposon using kanamycin selection, and reported the counts of amino-acid mutations for two biological replicates of the experiment. Here I have used dms_tools to infer the preferences. (A) Visualization of the preferences averaged across the two replicates. (B) Correlation between the preferences inferred from each of the two replicates. Given files containing the mutation counts, the plots can be generated as logoplot.pdf and corr.pdf with the following commands:.