Skip to main content
Figure 1 | BMC Bioinformatics

Figure 1

From: DisCons: a novel tool to quantify and classify evolutionary conservation of intrinsic protein disorder

Figure 1

Discons Work Flow. The schematic work flow of the DisCons sequence analysis pipeline is displayed along with a sample output table, showing the DisCons profile of human calpastatin domain I [Swiss-Prot:P20810]. The procedure starts either from a query sequence, followed by a BLASTP or PSI-BLAST search and the aligning of the retrieved sequences, or from a user-provided multiple sequence alignment. Next, position-specific sequence- and disorder conservation scores are calculated and finally these pairwise scores are combined to create the (aligned) DisCons profile. The result of one such classification is displayed at the bottom of the figure.

Back to article page

BMC Bioinformatics

ISSN: 1471-2105

Contact us