Table 4 Transitions of the Petri net of the IR model and the rate constants of the modeled reactions
From: MONALISA for stochastic simulations of Petri net models of biochemical systems
Transition | Reaction rate constant |
|---|---|
Bind_Insulin | 1·106 M −1 s −1 |
Diss_Insulin | 3.33·10−3 s −1 |
Inter_IR | 5.56·10−6 s −1 |
Phos_IR_I | 41.66s −1 |
Dephos_IR_I_P | 3.33·10−3 s −1 |
Inter_IR_I_P | 3.5·10−5 s −1 |
Deinter_IR_I_P | 3.5·10−6 s −1 |
Dephos_IR_I_P_Int | 7.68·10−3 |
Deinter_IR | 5·10−5 s −1 |
Degradation | 2.783·10−6 |
Synthesis | 2.78·10−19 M·s −1 |
if I R_I n t+I R_I_P_I n t≥10−13 M | |
Synthesis | 1.67·10−18 M·s −1 |
if I R_I n t+I R_I_P_I n t<10−13 M |