Skip to main content
Figure 1 | BMC Bioinformatics

Figure 1

From: Estimation of the methylation pattern distribution from deep sequencing data

Figure 1

The ‘true’ distribution Ξ k (black dots), observed read counts y k (blue pluses) and estimated distribution \( {\widehat{\theta}}_k \) from the slow (purple squares) and fast (red crosses) implementations of our algorithm over methylation patterns for synthetic data with n=6 CpG sites. The non-conversion rate is set to be Δ=0.005, the sequencing errors are set to be η=(0.008,0.006,0.006,0.006,0.006,0.008), the total number of reads is N read=2000. Only patterns with non-zero reads are shown and methylation patterns are ordered lexicographically. Data for the three patterns (000000, 111101 and 111111) which are beyond the range of the plot can be found in Table 1.

Back to article page