Figure 2
From: Estimation of the methylation pattern distribution from deep sequencing data
Comparison between the true distribution Ξ i , the simulated read distribution y i /N read, and the estimated distribution \( {\widehat{\theta}}_i \) for a synthetic dataset based on amplicon data. Parameter values are n=9 CpG sites, total number of reads N read=730, non-conversion parameter Δ=0.01, and sequencing error rate η=0.02. The lower plot is an expanded version of the upper plot showing only patterns with low frequencies.