Skip to main content
Figure 6 | BMC Bioinformatics

Figure 6

From: Topological characterization of neuronal arbor morphology via sequence representation: II - global alignment

Figure 6

Global consensus and local motifs. a. Plot of the k-mer percentile ranks (normalized frequencies), for each dimer and trimer of every cluster, with the cluster’s consensus values on the y-axis and the cluster’s average sequence values on the x-axis. The small correlation indicates that consensuses only capture a small proportion (14% of the variance) of the local motif information about the cluster’s members. b. Dimer profile (top) and consensus dendrograms (bottom) for clusters 1, 3, and 4. The dimer profile is similar between clusters 1 and 4, while the consensuses differ dramatically. c. Consensus dendrograms of cluster 4 neurite sequences, trimer-constrained surrogates of the sequences, and length-constrained surrogates of the sequences. Average normalized alignment scores are provided given a set of sequences aligned to a single consensus. Dendrogram branch widths show parent bifurcation’s conservation.

Back to article page