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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Error correction and statistical analyses for intra-host comparisons of feline immunodeficiency virus diversity from high-throughput sequencing data

Fig. 1

Histogram and simulated distributions: combined data. Minor allele (i.e. substitution) frequencies from all 12 libraries were pooled into the empirical distribution represented by the histogram. The dashed curve represents the distribution simulated from an exponential-normal convolution model with parameter values estimated on the data (Table 1). The solid curve represents the distribution simulated from the same model with parameters estimated on library pair 1 and 2 (Table 1) appropriately “spiked” with low frequency substitutions (see inset) to account for their abundance in high coverage sequencing data

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