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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Robust and automated three-dimensional segmentation of densely packed cell nuclei in different biological specimens with Lines-of-Sight decomposition

Fig. 1

Densely packed and apparently touching cell nuclei challenge segmentation procedures. Illustration of segmentation challenges for a three-dimensional section of densely packed and apparently touching cell nuclei. (a) Section of a raw gray-scale image taken from a CD1 mouse embryo labelled with DAPI. (b) Cell nuclei after intensity thresholding. (c) Touching sets of nuclei are assigned identical colors, indicating that they are wrongly detected as on object

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