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Fig. 2 | BMC Bioinformatics

Fig. 2

From: Evaluation of BLAST-based edge-weighting metrics used for homology inference with the Markov Clustering algorithm

Fig. 2

Illustration of simulated sequence fragmentation. This example illustrates the four different ways in which the fragmentation scheme 1323 would be applied to a toy input test database with only three clusters containing sequences from only four organisms. The four resulting test sets represent a cross of two variables, arranged here into rows and columns. The sequences in the top row (a & b) have been split into even subsequences. The sequences in the lower row (c & d) have been randomly fragmented into uneven subsequences. In the left column (a & c), the user-defined integer assigned to each organism directly determines the number of subsequences into which each sequence is split. In the right column (b & d), these integers are first mapped to all sequences within a cluster, but are then shuffled within that cluster before fragmentation

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