From: An evaluation of statistical methods for DNA methylation microarray data analysis
n | π 1 | Power | ||||||
---|---|---|---|---|---|---|---|---|
Rank test | t-test | KS test | Permutation | Empirical Bayes | Bump hunting BH | Bump hunting q-value | ||
3 | 0.01 | 0 | 0.0025 | 0 | 0 | 0.0000 | 0.0422 | 0.0539 |
0.05 | 0 | 0.0030 | 0 | 0 | 0.0000 | 0.0133 | 0.0166 | |
0.10 | 0 | 0.0027 | 0 | 0 | 0.0001 | 0.0116 | 0.0149 | |
0.25 | 0 | 0.0027 | 0 | 0 | 0.0002 | 0.0101 | 0.0132 | |
0.50 | 0 | 0.0031 | 0 | 0 | 0.0003 | 0.0100 | 0.0151 | |
0.75 | 0 | 0.0035 | 0 | 0 | 0.0004 | 0.0108 | 0.0196 | |
0.90 | 0 | 0.0038 | 0 | 0 | 0.0007 | 0.0115 | 0.0275 | |
6 | 0.01 | 0.0000 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0040 | 0.0043 |
0.05 | 0.0000 | 0.0003 | 0.0000 | 0.0000 | 0.0001 | 0.0013 | 0.0015 | |
0.10 | 0.0000 | 0.0002 | 0.0000 | 0.0000 | 0.0001 | 0.0008 | 0.0009 | |
0.25 | 0.0000 | 0.0002 | 0.0000 | 0.0000 | 0.0002 | 0.0007 | 0.0009 | |
0.50 | 0.0000 | 0.0002 | 0.0000 | 0.0000 | 0.0002 | 0.0006 | 0.0011 | |
0.75 | 0.0000 | 0.0003 | 0.0000 | 0.0000 | 0.0003 | 0.0007 | 0.0518 | |
0.90 | 0.0001 | 0.0003 | 0.0001 | 0.0001 | 0.0004 | 0.0007 | 0.8306 | |
12 | 0.01 | 0.0125 | 0.0002 | 0.0060 | 0.0000 | 0.0013 | 0.0012 | 0.0015 |
0.05 | 0.0201 | 0.0002 | 0.0071 | 0.0000 | 0.0008 | 0.0014 | 0.0017 | |
0.10 | 0.0429 | 0.0002 | 0.0172 | 0.0625 | 0.0008 | 0.0016 | 0.0021 | |
0.25 | 0.1291 | 0.0004 | 0.0828 | 0.3775 | 0.0013 | 0.0032 | 0.0099 | |
0.50 | 0.2566 | 0.0005 | 0.1935 | 0.5593 | 0.0194 | 0.0214 | 0.4811 | |
0.75 | 0.3560 | 0.0008 | 0.3004 | 0.6525 | 0.2526 | 0.1901 | 0.9410 | |
0.90 | 0.3894 | 0.0016 | 0.3010 | 0.6904 | 0.3945 | 0.3202 | 0.9993 | |
24 | 0.01 | 0.2000 | 0.0602 | 0.1955 | 0.0000 | 0.0779 | 0.1065 | 0.1111 |
0.05 | 0.3824 | 0.1561 | 0.5173 | 0.6587 | 0.1322 | 0.3315 | 0.3579 | |
0.10 | 0.4851 | 0.3883 | 0.5719 | 0.8010 | 0.3327 | 0.5460 | 0.5907 | |
0.25 | 0.6233 | 0.7138 | 0.7358 | 0.8928 | 0.6846 | 0.7914 | 0.8661 | |
0.50 | 0.7215 | 0.8666 | 0.8637 | 0.9394 | 0.8597 | 0.8997 | 0.9904 | |
0.75 | 0.7762 | 0.9197 | 0.9422 | 0.9577 | 0.9179 | 0.9326 | 1.0000 | |
0.90 | 0.7948 | 0.9380 | 0.9431 | 0.9649 | 0.9366 | 0.9407 | 1.0000 |