Table 2 FMs for target, Petalidis. Functional modules to facilitate functional mapping to target (Petalidis) variables from sources (Freije, Gravendeel, Paugh, Phillips, Sun, Yamanaka) variables
Clusters | GO Functional Theme | Markers |
|---|---|---|
FM1 | DNA repair | ADCY3, ADCY7, ALDH6A1, BLVRA, CSTF2T, DHX9, DNASE1L1, MCM2, MRE11A, STRAP, USP47 |
FM2 | Apoptotic processes | ADAMTSL4, ADORA1, ARAF, CASP5, CTSL2, FKTN, MCM2, MRE11A, P2RX1, RPS6KA3, SGPL1, STRN, TEX261, TRIAP1, USP47, VEGFA |
FM3 | Regulation of protein phosphorylation | ADCY3, ADCY7, ADORA1, ARAF, CDC37, DVL1, MRE11A, PPP2R5A, VEGFA |
FM4 | Cell differentiation | ACTG1, ALDH6A1, AP2B1, CRB1, DVL1, EFNB2, IFRD1, JAG1, MGP, MYO10, NHLH2, PBX1, RPS6KA3, RYR1, SGPL1, STRN, VEGFA, ZIC3, ZMYM3 |
FM5 | Transport | ABCC10, ADCY3, ADCY7, ADORA1, AP2B1, CDC37, LRMP, MSR1, MYO10, P2RX1, PDIA4, RYR1, VEGFA |
FM6 | Signal transduction | ADCY3, ADCY7, ADORA1, AP2B1, ARAF, CD97, CSNK1G1, CXCL6, DVL1, EFNB2, IGFBP2, JAG1, LANCL1, NDST1, P2RX1, PPP2R5A, RPS6KA3, SGPL1, STC1, STRN, VEGFA |
FM7 | Cell proliferation | IGFBP2, JAG1, MSR1, MYO10, PBX1, RPS6KA3, USP47, VEGFA |
FM8 | Response to glucose stimuli | ADCY3, ADCY7, CTSL2, CYP2E1, IGFBP2, JAG1, NDST1, P2RX1, RPS6KA3, RYR1, STC1, STRAP, VEGFA |
FM9 | Toll-like receptor signaling | RPS6KA3 |
FM10 | Transcription | ADCY7, BTAF1, DAZL, DVL1, FBN1, JAG1, MRE11A, NHLH2, NKRF, PBX1, RPS6KA3, STRAP, USP47, VEGFA, ZIC3, ZMYND11, ZNF187 |
FM11 | Response to stress | ACTG1, ADORA1, CASP5, CD97, CTSL2, CXCL6, DHX9, IGFBP2, LDHA, MRE11A, NDST1, NPEPPS, P2RX1, RPS6KA3, RYR1, STC1, TRIAP1, USP47, VEGFA |