Table 4 FMs for target, Lapointe. Functional modules to facilitate functional mapping to target (Lapointe) variables from sources (Nanni, Singh, Varambally, Wallace, Welsh, Yu) variables
Clusters | GO Functional Theme | Markers |
|---|---|---|
FM1 | Cardiac and urinary organ morphogenesis | ACTL6A, ANXA2, ERG, FZD7, GATA3, GATM, JUND, NFATC3, SOX9, WHSC1 |
FM2 | Lipid metabolism | ABCA2, AMACR, C3, GATA3, GATM, LEPR, NFATC3 |
FM3 | Regulation of chemokine production | C3, DARC, GATA3, SCGB1A1, SOX9 |
FM4 | Histone acetylation and methylation | ACTL6A, C3, GATA3, MUC1, NELL1, PRKCB, SOX9 |
FM5 | Signal transduction | ACTL6A, ADCY2, BCAM, C3, CCL1, DARC, DYNLT1, ERG, FZD7, GATA3, GDI1, GJA1, KCNN4, LEPR, MAP3K14, MUC1, PRKCB, RCAN2, SCGB1A1, SNAI2, SOX9, USP33, WIF1 |
FM6 | Chemotaxis | ABCA2, CCL1, GATA3, GATM, GDI1, JUND, SCGB1A1 |
FM7 | Transcription | ACTL6A, BCAS2, ERG, GATA3, GATM, JUND, NFATC3, NFYB, POLR2H, PRKCB, RPS29, WHSC1 |
FM8 | Regulation of transcription | ABCA2, ACTL6A, ETV5, FOSB, FZD7, GATA3, JUND, MUC1, NFATC3, NFYB, POLR2H, PRKCB, SCGB1A1, SNAI2, SOX9, TCEAL4, WHSC1 |
FM9 | Translation | DNAJC11, EEF2, ERG, MUC1, POLR2H, PRKCB, RPS29, USP33 |
FM10 | Cellular response to cytokines | ANXA2, DARC, FOSB, FZD7, GATA3, JUND, NFATC3, PRKCB, SOX9 |