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Table 2 Simulation parameters θ for spotted patterns in colon cancer tumors

From: POPE: post optimization posterior evaluation of likelihood free models

Parameter θ Description Mock A B C D E
κ W >0 Rate of nonlinear Wnt production 4 0.442 0.951 2.44 0.399 0.315
\(\kappa _{W_{I}} > 0\) Rate of Wnt inhibitor production 1 27.4 0.484 0.161 0.486 0.188
μ W ≥0 Decay rate of Wnt 2 0.642 0.179 0.791 0.545 0.936
\(\mu _{W_{I}} \geq 0\) Decay rate of Wnt inhibitor 4 2.36 1.30 1.10 0.569 1.064
a≥0 Constant of inhibition 10−8 0.4006 0.416 0.0384 0.00491 0.0284
b≥0 Constant of inhibition by W I 1 0.0125 7.94 20.05 0.616 0.640
S W ≥0 Rate of constitutive Wnt production 1 0.00167 0.00351 17.75 0.00005 0.00009
1≥D W >0 Diffusion coefficient of Wnt 0.01 0.0180 0.00322 0.0955 0.0336 0.0810
1≥N>0 Nutrient level 1 0.818 0.897 0.984 0.959 0.970