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Fig. 2 | BMC Bioinformatics

Fig. 2

From: Coevolutionary analyses require phylogenetically deep alignments and better null models to accurately detect inter-protein contacts within and between species

Fig. 2

Detecting coevolving alignment columns is easier when individual alignment columns have similar levels of variation. Column pairs in the HisKA-RR sub-alignments are parsed according to above- or below- median entropy for each size alignment size (number of sequences: N). Left: Median precision (PPV) at FPR < 0.1 %. Right: Median power (TPR) at FPR < 5 %. See Abbreviations and Table 1 for abbreviations

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BMC Bioinformatics

ISSN: 1471-2105

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