Fig. 4From: Coevolutionary analyses require phylogenetically deep alignments and better null models to accurately detect inter-protein contacts within and between speciesPower (TPR), precision (PPV), and false positive rate (FPR) for predicting antiviral protein A3G residues (not pairs) essential for interacting with its viral antagonist Vif at P empirical <α thresholds that maximize PPV for each coevolution method. Residues defined as positive are taken from previous functional mutation studies in Table 3. See Abbreviations and Table 1 for abbreviationsBack to article page