Table 7 Variables for Diffusion Coefficient of Microbicides from Mucoadhesive formulations [17]
From: A cascade computer model for mocrobicide diffusivity from mucoadhesive formulations
No | Loading dose (g/100 ml) | Gel weight (g) | pH of VFS | Flow rate (ml/hr) | Insertion Position (cm) | Q (%) |
|---|---|---|---|---|---|---|
1 | 3 | 1.5 | 4.0 | 3 | 5 | 58.6 |
2 | 3 | 1.5 | 4.0 | 3 | 15 | 45.5 |
3 | 3 | 1.5 | 4.0 | 3 | 5 | 35.9 |
5 | 3 | 1.5 | 4.0 | 5 | 15 | 76.9 |
8 | 3 | 1.5 | 5.5 | 3 | 15 | 25.8 |
11 | 3 | 1.5 | 5.5 | 5 | 15 | 40.8 |
14 | 3 | 1.5 | 7.4 | 3 | 15 | 2.0 |
20 | 3 | 3.0 | 4.0 | 3 | 15 | 24.3 |
23 | 3 | 3.0 | 4.0 | 5 | 15 | 59.0 |
26 | 3 | 3.0 | 5.5 | 3 | 15 | 34.5 |
29 | 3 | 3.0 | 5.5 | 5 | 15 | 34.2 |
38 | 5 | 1.5 | 4.0 | 3 | 15 | 26.4 |
44 | 5 | 1.5 | 5.5 | 3 | 15 | 16.6 |
47 | 5 | 1.5 | 5.5 | 5 | 15 | 31.2 |
64 | 5 | 3.0 | 5.5 | 5 | 15 | 25.7 |