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Table 8 The equations in various regression models used for the assessment of diffusion coefficient

From: A cascade computer model for mocrobicide diffusivity from mucoadhesive formulations

Methods

D

N

Higuchi Equation

(2*A*Cs*D*t)**1/2

7

D = 2.32 ± 0.80

Multivariate Regression I

D value = 2640.1023-186.17258*dose-202.39005*weight + 250.95155*flow_rate-275.11685*ph_value-48.67687*insert_pos

6

K-Nearest Neighbors

It predicts the D value as per the entered values of independent variables

 

Back Propagation Model

The network was trained for each number of hidden units for a given sample and the D value with the minimal PME was calculated.

 
  1. * Statistically significant (P < 0.05)