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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Robust sequence alignment using evolutionary rates coupled with an amino acid substitution matrix

Fig. 1

Comparison of the FIRE algorithm identity score distribution with CLUSTAL Omega and MAFFT algorithms for 100 alignments of low sequence similarity. Identity scores were calculated by normalising the number of matched residues to maximum sequence length. The FIRE score is the algorithm score for the aligned sequence based on the evolutionary rate approach. The divergence in identity score distributions between FIRE and the other algorithms reveals that the FIRE algorithm produces poor quality alignments compared to the conventional algorithms

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