Skip to main content
Fig. 2 | BMC Bioinformatics

Fig. 2

From: Robust sequence alignment using evolutionary rates coupled with an amino acid substitution matrix

Fig. 2

Alignment produced by the FIRE algorithm for simulated highly conserved sequences compared with conventional algorithms: CLUSTAL Omega, MAFFT and T-COFFEE. The first line in the FIRE output indicates the normalised score of ω score matches and the second line is the FIRE score for the alignment, FIRE scores above 0.6 indicate functional similarities in the sequences. The FIRE alignment demonstrates a false positive result

Back to article page