Fig. 6

Comparison of QuSAGE and Q-Gen analyses for the M1.2 Interferon gene set. Results are organized as follows: QuSAGE across the top, Q-Gen across the bottom. The left column provides the fold change estimates of testing changes over time relative to baseline, and the right column for testing symptomatic versus asymptomatic groups at each time point. Each comparison’s significance level is color coded based on its FDR adjusted p-value for that particular comparison across all 260 gene sets. Here, both method’s VIF are similar and thus provides a good comparison of just the difference between simple t-test procedures versus a linear mixed model. Q-Gen is able to detect differences over time and between groups a few time points earlier