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Table 4 The accuracy of secondary structure models predicted from tyrosyl-tRNA sequence (best values in bold)

From: New in silico approach to assessing RNA secondary structures with non-canonical base pairs

Method PPV TPR MCC
Variant I: Canonical and non-canonical base pairs
RNAwolf 0.71 0.44 0.56
MC-Fold-DP 0.41 0.33 0.37
MC-Fold 0.57 0.44 0.50
RC/Rp-1 0.94 0.74 0.83
RC/Rp-2 0.97 0.77 0.86
RC/Rp-3 0.94 0.77 0.85
Variant II: Canonical base pairs only
RNAwolf 0.80 0.76 0.78
MC-Fold-DP 0.28 0.43 0.35
MC-Fold 0.56 0.71 0.63
RC/Rp-1 0.95 1.00 0.98
RC/Rp-2 1.00 1.00 1.00
RC/Rp-3 1.00 1.00 1.00
Variant III: Non-canonical base pairs only, regardless of classification
RNAwolf 0.25 0.06 0.12
MC-Fold-DP n/a 0 n/a
MC-Fold 0.67 0.11 0.27
RC/Rp-1 0.89 0.44 0.63
RC/Rp-2 0.90 0.50 0.67
RC/Rp-3 0.82 0.50 0.64
Variant IV: Non-canonical base pairs only, classification dependent
RNAwolf 0.25 0.06 0.12
MC-Fold-DP n/a 0 n/a
MC-Fold 0.33 0.06 0.14
RC/Rp-1 0.78 0.39 0.55
RC/Rp-2 0.80 0.44 0.60
RC/Rp-3 0.55 0.33 0.43