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Fig. 7 | BMC Bioinformatics

Fig. 7

From: Extended notions of sign consistency to relate experimental data to signaling and regulatory network topologies

Fig. 7

Repair by adding signed influences example (Minimal Correction Sets - MCoS). There exist three alternative repair sets: repair set a adds a positive influence to A and repair set b includes a negative influence on B, repair set c includes a positive influence on A and a negative influence on B. Repair sets a and b are minimal containing only one repair, repair set c is not minimal having two repairs. Looking at the intersection of the labelings under minimal repairs, we can conclude that C is either responsible for an increase in A or a decrease in B. We can therefore exclude a labeling of C with 0, we can predict: p r e d(C)=±

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BMC Bioinformatics

ISSN: 1471-2105

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