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Table 2 Average % of unobserved nodes that have predictions of a particular behavior, their information gain and the precision for these predictions under the different notions giving 10 % or 50 % of the E. coli expression measurements as input. In the last major column (“all predictions”) the rows “% of unobserved nodes” quantify the overall recovery rates

From: Extended notions of sign consistency to relate experimental data to signaling and regulatory network topologies

Prediction

+ / −

0

Weak predictions / / ±

All predictions

Notion

FWP

SP

FSP

FWP

SP

FSP

FWP

SP

FSP

FWP

SP

FSP

Obtained using 10 % of the measurements as input.

 

% of unobserved nodes

0.13 %

2.60 %

2.91 %

1.19 %

46.43 %

53.64 %

7.74 %

12.99 %

13.14 %

9.06 %

62.03 %

69.70 %

Information gain

0.13 %

2.60 %

2.91 %

1.19 %

46.43 %

53.64 %

2.86 %

4.80 %

4.85 %

4.17 %

53.83 %

61.41 %

Precision of prediction

29.02 %

56.28 %

54.50 %

82.16 %

70.69 %

71.66 %

80.94 %

85.19 %

85.14 %

80.03 %

72.97 %

73.24 %

P -value

 

0.2791

1.0389e-08

8.0897e-10

Obtained using 50 % of the measurements as input.

 

% of unobserved nodes

0.48 %

3.06 %

3.08 %

4.84 %

67.93 %

72.30 %

28.99 %

7.27 %

7.07 %

34.31 %

78.26 %

82.45 %

Information gain

0.48 %

3.06 %

3.08 %

4.84 %

67.93 %

72.30 %

10.70 %

2.68 %

2.61 %

16.02 %

73.67 %

77.99 %

Precision of prediction

24.10 %

62.16 %

62.14 %

82.79 %

70.22 %

70.97 %

82.44 %

86.75 %

86.80 %

81.33 %

71.10 %

71.57 %

P -value

 

0.5

2.9782e-09

2.0785e-10